DC Chemicals · Product datasheet

PF-07328948 — Datasheet

CAT. NO. DC66611

Product page and current package options

ParameterValue
Chemical NamePF-07328948
CAS No.2936625-34-0
FormulaC16H8F4O3S
M.Wt356.29
SMILESFC1=C(C=C(C(F)=C1OC)C2=C(C(O)=O)SC3=CC(F)=CC=C23)F
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

PF-07328948 is a first-in-class branched-chain ketoacid dehydrogenase kinase (BDK) inhibitor with IC50 of 15 nM and shows a high degree selectivity over a number of kinases and other off-targets. PF-07328948 is the first known selective BDK inhibitor candidate to be examined in clinical studies.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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