Biological Activity
PS13 is a highly potent COX-1 inhibitor (IC50=1 nM) and 1,000 times more selective for COX-1 than COX-2 (7). In non-human primates, 11C-PS13 showed selective binding to COX-1 over COX-2 in most major organs including the spleen, gastrointestinal tract, kidneys, and brain.
In Vitro
No in vitro data are provided in the current product source. Contact us for further information.
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.