DC Chemicals · Product datasheet

D927 — Datasheet

CAT. NO. DC60864

Product page and current package options

ParameterValue
Chemical NameD927
SynonymsD-927,D 927,DS11252927
FormulaC23H21FN4O3S
M.Wt452.50
SMILESCOCCOC1=C(C2=NN=C(NC3=C(F)C=C(CC(N)=O)C=C3)C3=C2SC=C3)C=CC=C1
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

D927 is a molecular glue and promotes glucose uptake in the absence of insulin. D927 also increases the affinity of RAS binding to PI3Kα by ~500-fold. In vivo, D927 mimicks the effects of insulin and rapidly lowers blood glucose concentrations.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Cart

Request quotation