DC Chemicals · Product datasheet

VX-150 — Datasheet

CAT. NO. DC57073

Product page and current package options

ParameterValue
Chemical Name(4-(2-(4-Fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxopyridin-1(2H)-yl)methyl dihydrogen phosphate
CAS No.1793080-72-4
SynonymsBDBM186573;US9163042, VX-150;VX150 VX 150;EOS-62073;EOS62073;EOS 62073
FormulaC21H17F4N2O7P
M.Wt516.3363
SMILESP(=O)(O[H])(O[H])OC([H])([H])N1C([H])=C([H])C(=C([H])C1=O)N([H])C(C1C([H])=C([H])C(C(F)(F)F)=C([H])C=1OC1C([H])=C([H])C(=C([H])C=1C([H])([H])[H])F)=O
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

VX-150 is an orally active, highly selective NaV1.8 inhibitor. VX-150 has the potential for various pain indications research[1].

In Vitro

VX-150 is an orally bioavailable pro-drug that rapidly converts into its active moiety, which is a highly selective inhibitor of NaV1.8 relative to the other sodium channel subtypes (>400-fold)[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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