DC Chemicals · Product datasheet

Suvorexant — Datasheet

CAT. NO. DC5017

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ParameterValue
Chemical NameSuvorexant
CAS No.1030377-33-3
Synonyms(R)-(4-(5-Chlorobenzo[d]oxazol-2-yl)-7-methyl-1,4-diazepan-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone;Suvorexant MK4305;MK 4305;MK-4305;Suvorexant (MK-4305);[(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone;5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl]-1,3-benzoxazole;Suvorexant;[(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone;[(R)-4-(5-chlorobenzooxazol-2-yl)-7-methyl-[1,4]diazepan-1-yl](5-methy;5-chloro-2-{(5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}-1,3-benzoxazole;Belsomra?;DORA-analogue;EOS-61934;SUVOREXABT;MK-4305 (Suvorexant);Synonyms Suvorexant;Suvorexant (with 4 ints.);BELSOMRA;MK4305;081L192FO9;C23H23ClN6O2;((7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone;(R)-(4-(5-chlo
FormulaC23H23ClN6O2
M.Wt450.9207
SMILESClC1C([H])=C([H])C2=C(C=1[H])N=C(N1C([H])([H])C([H])([H])N(C(C3C([H])=C(C([H])([H])[H])C([H])=C([H])C=3N3N=C([H])C([H])=N3)=O)[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H])O2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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