DC Chemicals · Product datasheet

2OH-BNPP1 — Datasheet

CAT. NO. DC43769

Product page and current package options

ParameterValue
Chemical Name2OH-Bnpp1
CAS No.833481-73-5
SynonymsPhenol,2-[[4-amino-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]-;BCP29885;2-((4-amino-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenol
FormulaC16H19N5O
M.Wt297.354962587357
SMILESOC1C=CC=CC=1CC1C2=C(N)N=CN=C2N(C(C)(C)C)N=1
Purity>98%
Storage0°C (short term), -20°C (long term), desiccated

Biological Activity

2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

[1]. Nyati S, et al. The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. Sci Signal. 2015 Jan 6;8(358):ra1.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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