DC Chemicals · Product datasheet

Bexin-1 — Datasheet

CAT. NO. DC42587

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ParameterValue
Chemical NameBexin-1
CAS No.1172933-44-6
SynonymsBexin-1;N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1-ethyl-5-methyl-1H-pyrazole-3-carboxamide
FormulaC20H26ClN5OS
M.Wt419.971341609955
SMILESClC1=CC=C(C)C2=C1SC(=N2)N(C(C1C=C(C)N(CC)N=1)=O)CCCN(C)C
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Bexin-1 is a specific inhibitor that targets Munc13-4, a protein critical for regulated exocytosis, particularly in secretory cells such as immune cells (e.g., cytotoxic T lymphocytes, mast cells) and neuroendocrine cells. Munc13-4 plays a key role in vesicle priming and fusion with the plasma membrane, a process essential for the release of secretory granules containing hormones, neurotransmitters, or immune mediators.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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