MC-DM1 Datasheet | DC40875

MC-DM1 — Datasheet

CAT. NO. DC40875

Parameter	Value
Chemical Name	MC-DM1
CAS No.	1375089-56-7
Formula	C42H55ClN4O12
M.Wt	843.36
SMILES	C[C@]1([C@H](CC(N(C(C=C(C2)C=C3OC)=C3Cl)C)=O)OC([C@H](C)N(C)C(CCCCCN(C4=O)C(C=C4)=O)=O)=O)[C@@]([C@@H]([C@](OC5=O)([H])C[C@]([C@@H](/C=C/C=C2\C)OC)(N5)O)C)([H])O1
Purity	>98%
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Biological Activity

MC-DM1 is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody drug conjugate (ADC)[1].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

Maytansinoids

References & source

[1]. Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.