DC Chemicals · Product datasheet

LDC203974(IMT1B) — Datasheet

CAT. NO. DC39817

Product page and current package options

ParameterValue
Chemical Name3-​Piperidinecarboxylic acid, 1-​[(2R)​-​2-​[[4-​(2-​chloro-​4-​fluorophenyl)​-​2-​oxo-​2H-​1-​benzopyran-​7-​yl]​oxy]​-​1-​oxopropyl]​-​, (3S)​-
CAS No.2304621-06-3
SynonymsLDC203974;LDC 203974;LDC-203974;IMT1B,IMT1-B IMT1 B
FormulaC24H21ClFNO6
M.Wt473.88
SMILESC1(C(Cl)=CC(F)=CC=1)C1=CC(=O)OC2=C1C=CC(=C2)O[C@@H](C(=O)N1CCC[C@H](C(=O)O)C1)C
Purity>99%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

LDC203974(IMT1B) is a highly specific inhibitor of human mitochondrial RNA polymerase (POLRMT) with improved pharmacokinetic profiles than LDC195943(IMT1).

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

Small-molecule inhibitors of human mitochondrial DNA transcription-Nature,Published: 16 December 2020

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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