DC Chemicals · Product datasheet

SBP-7455 — Datasheet

CAT. NO. DC39262

Product page and current package options

ParameterValue
Chemical Name2,​4-​Pyrimidinediamine, N4-​cyclopropyl-​N2-​(3,​4-​dimethoxyphenyl)​-​5-​(trifluoromethyl)​-
CAS No.1884222-74-5
SynonymsSBP-7455;SBP 7455;SBP7455
FormulaC16H17F3N4O2
M.Wt354.33
SMILESC1N=C(NC2C=CC(OC)=C(OC)C=2)N=C(NC2CC2)C=1C(F)(F)F
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

SBP-7455 is an orally active dual-specific ULK1/2 autophagy inhibitor with improved binding affinity compared with SBI-0206965.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

1 Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer--Huiyu Ren 1, Nicole A Bakas 1, Mitchell Vamos 1, Ap

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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