DC Chemicals · Product datasheet

CCS-1477(CBP-IN-1) — Datasheet

CAT. NO. DC31451

Product page and current package options

Parameter	Value
Chemical Name	Inobrodib
CAS No.	2222941-37-7
Synonyms	CBP-IN-1;(S)-1-(3,4-Difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4S)-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one;CBP/p300-IN-4;Inobrodib;2-Piperidinone, 1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]-, (6S)-;D12394;SCHEMBL20094038;GTPL13063;Ccs 1477;SCHEMBL22134021;BDBM50602864;WHO 11833;Inobrodib [INN];CCS-1477 (CBP-IN-1);(6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one;SCHEMBL21515367;AKOS040732748;MS-29881;CCS-1477(CBP-IN-1)?;G16679;Inobrodib (USAN);NSC818619;CCS1477;CBP-IN-1;CBP/p300-IN-4;EX-A3687;2222941-37-7;SCHEMBL23433835;CHEMBL4785363;NSC-818619;BW5QA5GEW7;(6S)-1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one;(S)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-(4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one;HY-111784;DA-71991;CBP-?IN-?1;(6S)-1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1r,4r)-4-methoxycyclohexyl]-1,3-benzodiazol-2-yl]piperidin-2-one;CCS-1477;CCS1477; Inobrodib;CCS1477;UNII-BW5QA5GEW7;(6S)-1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]piperidin-2-one;s9667;(S)-1-(3,4-Difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-(trans-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one;CCS 1477 [WHO-DD];GLXC-26849;2-Piperidinone, 1-(3,4-difluorophenyl)-6-(5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl)-, (6S)-;JHL;CS-0091862;(S)-1-(3,4-Difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1R,4S)-4-methoxycyclohexyl)-1H-benzo(d)imidazol-2-yl)piperidin-2-one;Inobrodib [USAN];Inobrodib [USAN:INN];P300/cbp bromodomain inhibitor CCS1477
Formula	C30H32F2N4O3
M.Wt	534.5969
SMILES	FC1=C(C([H])=C([H])C(=C1[H])N1C(C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC2C([H])=C(C3C(C([H])([H])[H])=NOC=3C([H])([H])[H])C([H])=C([H])C=2N1C1([H])C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])OC([H])([H])[H])=O)F
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

CCS-1477(CBP-IN-1) is a potent p300/CBP bromodomain inhibitor[1].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

p300/CBP[1]

References & source

[1]. Neil Anthony Pegg, et al. Pharmaceutical compounds. WO2018073586A1.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.