DC Chemicals · Product datasheet

Idoxuridine — Datasheet

CAT. NO. DC31184

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ParameterValue
Chemical NameIdoxuridine
CAS No.54-42-2
Synonyms5-Iodo-2'-deoxyuridine;2-Deoxy-5-iodouridine;Idoxuridine;IDU;(+)-5-Iodo-2'-deoxyuridine;1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione;5-iodo-2’-Deoxyuridine;(+)-5-Iodo-2-Deoxyuridine;1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil;5-Iodo-2′-deoxyuridine;5-IUdR;IdUrd;2′-Deoxy-5-iodouridine;5-Iododesoxyuridine;2'-Deoxy-5-iodouridine;5-IdU;5-Iododeoxyuridine;Idoxuridin;Iododeoxyridine;Iodoxuridine;IUDR;Joddeoxiuridin;Idoxene;Herpid;Dendrid;Stoxil;Herplex;Allergan 211;IDUR;Virudox;Iduridin;Kerecid;5IUDR;Herplex liquifilm;Idoxuridinum;Spectanefran;Iduviran;Idoxuridina;Antizona;Idexur;Iducher;Idulea;Heratil;Allergan 201;Idossuridina [DCIT];Idu Oculos;5-Iodouracil deoxyriboside;Iduoculos;1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodo;BPBio1_000061;BSPBio_000055;Tox21_110324_1;BRD-K76634210-001-14-7;Idoxuridina [INN-Spanish];1beta-D-2'-Deoxyribofuranosyl-5-iodouracil;NCGC00179673-03;URIDINE, 2'-DEOXY-5-IODO-;J-700180;DB00249;4-24-00-01235 (Beilstein Handbook Reference);Oftan-IDU;5-I-2'-dUrd;Epitope ID:138107;Kerecide;Idoxuridine [USAN:USP:INN:BAN:JAN];Q409765;Allergan-211;2'-DESOXY-5-IODOURIDINE;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione;Idossuridina;AC-8219;Emanil;Uracil, 5-iodo-1-(2-deoxy-beta-D-ribofuranosyl)-;NSC 39661;MFCD00134656;HMS2095C17;HMS2230E10;LS-160825;CCRIS 2827;1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil;5-Iodo-2 inverted exclamation marka-deoxyuridine;IDOXURIDINE [WHO-DD];Idoxuridine [USAN:BAN:INN:JAN];IDOXURIDINE [JAN];Herpidu;5-IODO-2-DEOXYURIDINE;IDOXURIDINE [WHO-IP];Idoxuridinum [INN-Latin];1-(2-Deoxy-ss -D-ribofuranosyl)-5-iodouracil;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione;Ophthalmadine;NSC-39661;s1883;J-009907;AKOS015920431;IDOXURIDINE [ORANGE BOOK];Idoxuridine, European Pharmacopoeia (EP) Reference Standard;5-Iodo-deoxyuridine;SK&F-14287;BCP29428;BP-58646;HMS3712C17;NCGC00179673-05;AI3-50861;ALLERGAN211;HY-B0307;I0258;IDOXURIDINE [MART.];SCHEMBL3683;54-42-2;DTXCID0025238;LGP81V5245;SR-05000001510-1;CCG-220018;Idoxuridine (JP17/USP/INN);AS-13469;IDOXURIDINE [USP MONOGRAPH];1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil;IDOXURIDINUM [WHO-IP LATIN];SK& 14287;CAS-54-42-2;Idoxuridine 100 microg/mL in Acetonitrile;C9H11IN2O5;SR-05000001510-4;D00342;XQFRJNBWHJMXHO-RRKCRQDMSA-N;5-IUdR; IDU; IdUrd; Idoxuridine;DTXSID2045238;ID2;CHEMBL788;5-Iodo-2'-deoxyuridine, >=99% (HPLC);BRN 0030397;IDOXURIDINE [USP-RS];SMP2_000072;Herpesil;Tox21_110324;1-(4-Hydroxy-5-hydroxymethyltetrahydrofuran-2-yl)-5-iodo-1H-pyrimidine-2,4-dione;SW198484-2;Synmiol;UNII-LGP81V5245;SK&F 14287;Idoxuridine [USAN:INN:BAN:JAN];IDOXURIDINE [EP MONOGRAPH];Iododeoxyuridine;HMS2090M10;IDOXURIDINE [INN];5IdU;D02IED;IDOXURIDINE [MI];IDOXURIDINE [USP IMPURITY];EINECS 200-207-8;NCGC00179673-01;5-iodo-2'deoxyuridine;Prestwick3_000018;SR-...
FormulaC9H11IN2O5
M.Wt354.0985
SMILESIC1C(N([H])C(N(C=1[H])[C@@]1([H])C([H])([H])[C@@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])=O)=O
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Idoxuridine is an anti-herpesvirus antiviral and anticancer drug. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to cardiotoxicity. It was synthesized by William Prusoff in the late 1950s. Initially developed as an anticancer drug, idoxuridine became the first antiviral agent in 1962.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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