DC Chemicals · Product datasheet

Tivozanib (hydrate) — Datasheet

CAT. NO. DC31068

Product page and current package options

ParameterValue
Chemical NameN-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-urea,monohydrate
CAS No.682745-40-0
SynonymsUrea, N-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-, monohydrate (9CI)
FormulaC22H21ClN4O6
M.Wt472.878344297409
SMILESO(C1C=CC(NC(=O)NC2=NOC(C)=C2)=C(Cl)C=1)C1=CC=NC2C=C(OC)C(OC)=CC1=2.O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Tivozanib is an orally available, selective VEGFR inhibitor with IC50 values of 0.21, 0.16, and 0.24 nM for VEGFR1, VEGFR2, and VEGFR3, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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