DC Chemicals · Product datasheet

Mobocertinib(TAK-788) — Datasheet

CAT. NO. DC28953

Product page and current package options

ParameterValue
Chemical NameMobocertinib free base
CAS No.1847461-43-1
SynonymsAP-32788,AP32788,AP 32788,TAK 788,TAK788,TAK-788
FormulaC32H39N7O4
M.Wt585.71
SMILESO=C(OC(C)C)C1C(C2C3C=CC=CC=3N(C)C=2)=NC(NC2C(OC)=CC(N(C)CCN(C)C)=C(NC(=O)C=C)C=2)=NC=1
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Mobocertinib is a potent epidermal growth factor receptor (EGFR) inhibitor and an antineoplastic agent, extracted from patent WO2019222093A1, compound A[1][2].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

[1]. Francois Gonzalvez, et al. Abstract 2644: AP32788, a potent, selective inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, in preclinical models. April 16-20, 2016; New Orleans, LA.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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