DC Chemicals · Product datasheet

VKGILS-NH2 — Datasheet

CAT. NO. DC26220

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ParameterValue
Chemical NameVKGILS-NH2
CAS No.942413-05-0
SynonymsVKGILS-NH2;PAR-2 (6-1) amide (human);L-Valyl-L-lysylglycyl-L-isoleucyl-L-leucyl-L-serinamide (ACI);L
FormulaC28H54N8O7
M.Wt614.777766704559
SMILES[C@H](CC(C)C)(C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)C(C)C
Purity>98%
Storage2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

Biological Activity

VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells[1][2].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

Bohm et al (1996) Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem.J. 314 1009 PMID: 8615752

Hollenberg and Compton (2002) International union of pharmacology XXVIII. Proteinase-activated recepto

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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