DC Chemicals · Product datasheet

Triptorelin — Datasheet

CAT. NO. DC24126

Product page and current package options

ParameterValue
Chemical NameLuteinizing hormone-releasing factor (swine), 6-D-tryptophan-
CAS No.57773-63-4
Synonyms[DTrp6]-LH-RH
FormulaC64H82N18O13
M.Wt1311.449
SMILESNC(NCCC[C@@H](C(N1CCC[C@H]1C(NCC(=O)N)=O)=O)NC([C@@H](NC([C@@H](CC1=CNC2=CC=CC=C12)NC([C@@H](NC([C@@H](NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@@H](NC([C@@H]1CCC(=O)N1)=O)CC1=CN=CN1)=O)=O)CO)=O)CC1=CC=C(O)C=C1)=O)=O)CC(C)C)=O)=N
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

(1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.

References & source

[1]. Wei S et al. Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice. Immunopharmacol Immunotoxicol. 2016 Jun;38(3):197-204.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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