Biological Activity
STD-101-D1 is a novel brain permeable, G protein-biased beta-1 adrenergic receptor (ADRB1) partial agonist with EC50 of 16.9 nM; engages very little beta-arrestin recruitment compared to the unbiased agonist isoproterenol; also inhibits the acute peripheral and CNS TNFα response induced by LPS both in vitro and in vivo.
In Vitro
No in vitro data are provided in the current product source. Contact us for further information.
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
References & source
References 1. Yi B, et al. PLoS One. 2017 Jul 26;12(7):e0180319. View Related Products by Target Adrenergic Receptor
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.