E3 ligase Ligand 1A ((S,R,S)-AHPC-Me) Datasheet | DC22335

E3 ligase Ligand 1A ((S,R,S)-AHPC-Me) — Datasheet

CAT. NO. DC22335

Parameter	Value
Chemical Name	E3 ligase Ligand 1A ((S,R,S)-AHPC-Me)
CAS No.	1948273-02-6
Synonyms	E3 ligase Ligand 1A
Formula	C23H32N4O3S
M.Wt	444.60
SMILES	Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](N)C(C)(C)C)cc1
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Chemical identity references

Biological Activity

E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

[1]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.