DC Chemicals · Product datasheet

ALG1001 (Risuteganib) — Datasheet

CAT. NO. DC22211

Product page and current package options

ParameterValue
Chemical NameLuminate
CAS No.1307293-62-4
Synonyms123DNA66IA;Risuteganib;Luminate;Risuteganib [USAN];ALG1001;Glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-L-proline;L-Proline, glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-
FormulaC22H39N9O11S
M.Wt637.666
SMILESS(C[C@@H](C(N[C@@H]([C@@H](C)O)C(N1CCC[C@H]1C(=O)O)=O)=O)NC(CNC([C@H](CCC/N=C(\N)/N)NC(CN)=O)=O)=O)(=O)(=O)O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis; ALG1001 inhibits an integrin-mediated pathway of the vitreoretinal interface, connecting the posterior aspect of the vitreous with the internal limiting membrane of the retina. In blocking this pathway, ALG-1001 helps to achieve vitreous breakdown and separation from the retina.

Other Indication

Phase 2 Clinical

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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