DC Chemicals · Product datasheet

ATF6 agonist compound A147 — Datasheet

CAT. NO. DC21979

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ParameterValue
Chemical NameN-(2-hydroxy-5-methylphenyl)-3-phenylpropanamide
CAS No.393121-74-9
SynonymsAA147|AA 147;AA-147
FormulaC16H17NO2
M.Wt255.31
SMILESO=C(CCC1C=CC=CC=1)NC1C(O)=CC=C(C)C=1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

AA147, a small molecule endoplasmic reticulum (ER) proteostasis regulator, selectively activates ATF6 arm of the unfolded protein response (UPR) extracted from patent WO2017117430A1, compound 147*[1].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

PNAS January 19, 2021 118 (3) eiti0221118; https://doi.org/10.1073/iti0321118. Small-molecule endoplasmic reticulum proteostasis regulator acts as a broad-spectrum inhibitor of dengue and Zika virus infections

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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