DC Chemicals · Product datasheet

4-CPPC — Datasheet

CAT. NO. DC21978

Product page and current package options

ParameterValue
Chemical Name4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid
CAS No.29553-70-6
Synonyms4-CPPC|4CPPC
FormulaC14H9NO6
M.Wt287.227
SMILESO=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

1. Pantouris G, et al. Biochemistry. 2018 Jun 12. doi: 10.1021/acs.biochem.8b00344.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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