DC Chemicals · Product datasheet

Danicamtiv (MYK-491) — Datasheet

CAT. NO. DC21881

Product page and current package options

ParameterValue
Chemical Name4-{(1R)-1-[3-(difluoromethyl)-1-methyl-1H-pyrazole-4-sulfonyl]-1-fluoroethyl}-N-(1,2-oxazol-3-yl)piperidine-1-carboxamide
CAS No.1970972-74-7
SynonymsDanicamtiv|MYK491|MYK-491|MYK 491
FormulaC16H20F3N5O4S
M.Wt435.422
SMILESFC(C1CCN(C(NC2=NOC=C2)=O)CC1)(C)S(C3=CN(C)N=C3C(F)F)(=O)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Danicamtiv is a positive inotropic agent.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

[1]. Sarah Fernandes, et al. Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence. Circulation. 2019;140:A15707

[2]. V

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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