DC Chemicals · Product datasheet

UU-T02 — Datasheet

CAT. NO. DC21786

Product page and current package options

ParameterValue
Chemical Name(S)-4-((S)-3-carboxy-2-((S)-2-(2-(5-chloro-1H-indol-2-yl)acetamido)-3-(naphthalen-2-yl)propanamido)propanamido)-5-methoxy-5-oxopentanoic acid
CAS No.1500080-17-0
SynonymsUU-T02; UU-T-02; UU-T 02; UUT02; UUT-02; UUT 02
FormulaC33H33ClN4O9
M.Wt665.096
SMILESO=C(O)CC[C@H](NC([C@@H](NC([C@@H](NC(CC(N1)=CC2=C1C=CC(Cl)=C2)=O)CC3=CC=C4C=CC=CC4=C3)=O)CC(O)=O)=O)C(OC)=O
Purity>97%
Storage2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

Biological Activity

UU-T02 is a novel potent, selective small-molecule inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; displays 63-fold and 175-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

References 1. Huang Z, et al. ACS Chem Biol. 2014 Jan 17;9(1):193-201. View Related Products by Target Beta-catenin

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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