DC Chemicals · Product datasheet

MLS 0263839 — Datasheet

CAT. NO. DC21329

Product page and current package options

ParameterValue
Chemical NameN,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide
CAS No.716375-92-7
SynonymsN,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide;MLS000773738;MLS003116069;KUC104125N;SMR000364449;MLS002460504;BDBM34966;cid_5040456;HMS2218K20;HMS3340G17;VU0316361-2;Q27164871;Z56798522;3-(3-keto-1,2-benzothiazol-2-yl)-N,N-dimethyl-benzenesulfonamide;N,N-dimethyl-3-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzenesulfonamide;N,N-Dimethyl-3-(
FormulaC15H14N2O3S2
M.Wt334.413260936737
SMILESS(C1C=CC=C(C=1)N1C(C2C=CC=CC=2S1)=O)(N(C)C)(=O)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

MLS 0263839 is a potent, specific inhibitor of the phosphatase PHOSPHO1 with IC50 of 0.14 uM, shows minimal cross-inhibition of TNAP and no inhibition of ENPP1 activity; suppresses vascular smooth muscle cell calcification in cimbined with MLS 0038949.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

References 1. Kiffer-Moreira T, et al. J Bone Miner Res. 2013 Jan;28(1):81-91. 2. Huesa C, et al. Biochem Biophys Rep. 2015 Dec 1;4:196-201. View Related Products by Target Protein Phosphatase/PTP

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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