DC Chemicals · Product datasheet

BDCRB — Datasheet

CAT. NO. DC21101

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ParameterValue
Chemical NameBdcrb
CAS No.142356-43-2
SynonymsBDCRB;(2R,3R,4S,5R)-2-(2-bromo-5,6-dichloro-benzimidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;1038U90U*J;2-bromo-5,6-dichloro-1-([-]-carbocyclic) benzimidazole;2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole;2-Bromo-5,6-dichloro-1-.beta.-D-ribofuranosylbenzimidazole;(2R,3R,4S,5R)-2-(2-Bromo-5,6-dichloro-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
FormulaC12H11BrCl2N2O4
M.Wt398.036740541458
SMILESBrC1=NC2C=C(C(=CC=2N1[C@H]1[C@@H]([C@@H]([C@@H](CO)O1)O)O)Cl)Cl
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

BDCRB (GW 275175) is a potent and selective inhibitor of human CMV replication by blocking the processing and maturation of viral DNA.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

Townsend LB, et al. J Med Chem. 1995 Sep 29;38(20):4098-105. 2. Underwood MR, et al. J Virol. 1998 Jan;72(1):717-25. 3. Nassiri MR, et al. Br J Haematol. 1996 May;93(2):273-9. 4. Williams SL, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92. View Related Products by Target CMV

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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