DC Chemicals · Product datasheet

4-Butylresorcinol — Datasheet

CAT. NO. DC20186

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ParameterValue
Chemical Name4-Butylresorcinol
CAS No.18979-61-8
Synonyms4-Butylbenzene-1,3-diol;4-N-BUTYLRESORCINOL;2,4-DIHYDROXY-N-BUTYL BENZENE;2,4-DIHYDROXY-N-BUTYL BENZEN;2,4-Dihydroxy-n-bytyl benzen;4-Butylresorcinol;1-butyl-2,4-dihydroxybenzene;4-Butylresorcin;4-butyl-resorcinol;Butylresorcinol;N-butylresorcinol;Resorcinol,4-butyl;4-Butyl-1,3-benzenediol;N-BUTYLRESEOCINOL;4-phenylbutane-1,3-diol;1,3-Benzenediol,4-butyl-;Resorcinol, 4-butyl-;Rucinol;2IK4UQ3ZGA;1,3-Benzenediol, 4-butyl-;Kopcinol;4-(2,4-dihydroxyphenyl)butane;n-butyl resorcinol;Rucinol (TN);D;4-BUTYLRESORCINOL,98+%
FormulaC10H14O2
M.Wt166.2170
SMILESO([H])C1C([H])=C(C([H])=C([H])C=1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])O[H]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

In Vitro It shows that 4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. In addition, it is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression. 4-Butylresorcinol strongly reduces tyrosinase activity in a cell-free system. Moreover, 4-Butylresorcinol shows an additive effect in combination with hinokitiol, which reduces MITF expression.

In Vitro

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In Vivo

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References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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