DC Chemicals · Product datasheet

Benznidazole (Synonyms: Benznidazol; Ro 07-1051; Ro 71051) — Datasheet

CAT. NO. DC20028

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ParameterValue
Chemical NameBenznidazol
CAS No.22994-85-0
Synonyms1H-Imidazole-1-acetamide,2-nitro-N-(phenylmethyl)-;Benznidazole;N-Benzyl-2-Nitro-1H-Imidazole-1-Acetamide;N-benzyl-2-(2-nitroimidazol-1-yl)acetamide;Radanil;Benzonidazole;Benznidazol;benzonidazol;Benznidazolum;N-Benzyl-2-nitroimidazole-1-acetamide;N-Benzyl-2-nitroimidazol-1-yl-acetamide;Rochagan;Benznidazolum [INN-Latin];Benznidazol [INN-Spanish];1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-;Ro 71051;N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide;2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide;Imidazole-1-acetamide, N-be;Ro 07-1051;N-Benzyl-2-nitro-1H-imidazole-1-acetamide;1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)- [;CS-0013411;CCG-267054;BENZNIDAZOLE (MART.);AKOS024283499;Tox21_112364;N-benzyl-2-(2-nitro-1Himidazol-1-yl)acetamide;MLS001360496;CHEMBL110;J-014932;P01CA02;benznidazole (TN);HMS3369C11;BDBM50089916;Benznidazole [INN];BENZNIDAZOLE [USAN];BENZNIDAZOLE [ORANGE BOOK];NSC-299972;AS-68694;1H-Imidazole-1-acetamide,2-Nitro-n-(phenylmethyl)-;D02489;YC42NRJ1ZD;SR-01000841264;NSC 299972;NSC299972;Benznidazolum (INN-Latin);N-benzyl-2-nitro-1-imidazoleacetamide;SR-01000841264-3;C74184;CCRIS 2200;Rochagan (TN);RO-07-1051;Imidazole-1-acetamide, N-benzyl-2-nitro-;A912716;BENZNIDAZOLUM [WHO-IP LATIN];22994-85-0;BRD-K56156805-001-05-4;Acetamide, N-benzyl-2-(nitroimidazol-1-yl)-;SMR000857153;HMS2233G13;Pyridinium,1-dodecyl-2-[(hydroxyimino)methyl]-,iodide(1:1);NCGC00166238-01;DTXCID7026570;MLS001332409;EN300-1716737;HY-B1548;s3741;N-Benzyl-2-(2-nitro-imidazol-1-yl)-acetamide;CHEBI:133833;UNII-YC42NRJ1ZD;DB11989;Q425300;CAS-22994-85-0;Ragonil;MMV688773;MFCD00243089;Benznidazol (INN-Spanish);MLS001332410;BENZNIDAZOLE;AKOS015916722;SCHEMBL45081;BENZNIDAZOLE [MART.];Ro 07-1051;Ro 71051;SCHEMBL22493029;Tox21_112364_1;NS00068191;NCGC00166238-02;BENZNIDAZOLE [MI];N-Benzyl-2-(2-nitro-imidazol-1-yl)-acetamide (Benznidazole);SR-01000841264-4;BENZNIDAZOLE [WHO-IP];BENZNIDAZOLE [WHO-DD];Z2044771577;DTXSID9046570;Radanil (TN);Benznidazol (Ro 07-1051; Ro 71051);BRN 0551486;Ro-7-1051;N-benzyl-2-(2-nitro-1H-imidazol-5-yl)acetamide;N-Benzyl-2-nitro-1H-imidazole-1-acetamide, 97%;FT-0662547;Benznidazole (USAN/INN);Benznidazole [USAN:INN]
FormulaC12H12N4O3
M.Wt260.2487
SMILESO=C(C([H])([H])N1C([H])=C([H])N=C1[N+](=O)[O-])N([H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

In Vivo Benznidazole (100 mg/kg/day, p.o., 30 days) produces a decrease in electrocardiographic alterations, fewer modifications in the affinity and density of cardiac-receptors, and few isolated areas of fibrosis in the heart, in mice infected with Trypanosoma cruzi Tulahuen strain or SGO-Z12 isolate and treated at 180 days post infection (p.i.) (i.e. chronic phase) with Benznidazole.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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