SCR-1481B1 (BMS-817378, bis-Tris salt) Datasheet | DC12667

SCR-1481B1 (BMS-817378, bis-Tris salt) — Datasheet

CAT. NO. DC12667

Parameter	Value
Chemical Name	SCR-1481B1 (BMS-817378, bis-Tris salt)
CAS No.	1174161-86-4
Synonyms	SCR-1481B1(BMS-817378 tris salt)
Formula	C32H40ClF2N6O13P
M.Wt	821.12
SMILES	NC(CO)(CO)CO.NC(CO)(CO)CO.Nc1nccc(Oc2ccc(NC(=O)c3cn(COP(=O)(O)O)cc(-c4ccc(F)cc4)c3=O)cc2F)c1Cl
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Structure and molecular-weight basis	Bis-Tris salt: 1 SCR-1481B1 molecule and 2 Tris molecules. Formula and M.Wt refer to the complete 1:2 unit.

Chemical identity references

Biological Activity

SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.

In Vitro

More details please refer to Patent WO 2009094417 A1.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

VEGFR1

References & source

[1]. Robert M. Borzilleri, et al. 4-pyridinone compounds and their use for cancer. WO/2009094417/A1.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.