DC Chemicals · Product datasheet

Apararenone — Datasheet

CAT. NO. DC12636

Product page and current package options

ParameterValue
Chemical NameN-(4-(4-fluorophenyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)methanesulfonamide
CAS No.945966-46-1
SynonymsMT-3995;MT3995
FormulaC17H17FN2O4S
M.Wt364.391
SMILESCS(NC1C=C2C(=CC=1)N(C1=CC=C(F)C=C1)C(=O)C(C)(C)O2)(=O)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Apararenone (MT-3995) is a novel non-steroidal mineralocorticoid receptor antagonists under development for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

Recently, a phase II clinical trial has been initiated among patients with non-alcoholic steatohepatitis (NASH) in Japan[1].

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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