Biological Activity
MDI-2268 (MDI2268) is a small-molecule, in vivo-active inhibitor of plasminogen activator inhibitor type-1 (PAI-1), demonstrates excellent pharmacokinetics, potent activity against vitronectin-bound PAI-1 in vivo, and efficacy in murine model of venous thrombosis.
In Vitro
No in vitro data are provided in the current product source. Contact us for further information.
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
References & source
References 1. Reinke AA, et al. J Biol Chem. 2018 Dec 3. pii: jbc.RA118.004885. doi: 10.1074/jbc.RA118.004885. View Related Products by Target Plasminogen Activator Inhibitor-1 (PAI-1)
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.