DC Chemicals · Product datasheet

DC661 — Datasheet

CAT. NO. DC12554

Product page and current package options

ParameterValue
Chemical NameN1-(7-Chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine
CAS No.1872387-43-3
SynonymsDC661;N-(7-Chloroquinolin-4-yl)-N'-[6-[(7-chloroquinolin-4-yl)amino]hexyl]-N'-methylhexane-1,6-diamine;N1-(7-chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine;BCP30743;s8808;ZB1540
FormulaC31H39Cl2N5
M.Wt552.5809
SMILESClC1C([H])=C([H])C2C(C=1[H])=NC([H])=C([H])C=2N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1C([H])=C([H])N=C2C([H])=C(C([H])=C([H])C=12)Cl
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1].

In Vitro

DC661 (0.1 and 10 µM) accumulates autophagic vesicles in melanoma cells[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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