DC Chemicals · Product datasheet

BI-0314 — Datasheet

CAT. NO. DC12406

Product page and current package options

ParameterValue
Chemical Name1-(3-(piperidin-4-yl)-5-(trifluoromethyl)phenyl)guanidine
CAS No.2244560-46-9
SynonymsBI0314;BI 0314
FormulaC13H17F3N4
M.Wt286.302
SMILESN(C1=CC(C(F)(F)F)=CC(C2CCNCC2)=C1)C(=N)N
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

BI-0314 (BI0314) is an allosteric activator of protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) with potency of 56% at 500 uM, displays no activity against hPTP1B and hTCPTP.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

References 1. Tautermann CS, et al. J Med Chem. 2018 Sep 12. doi: 10.1021/acs.jmedchem.8b00857. View Related Products by Target Protein Phosphatase/PTP

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Cart

Request quotation