DC Chemicals · Product datasheet

BOS172722 — Datasheet

CAT. NO. DC12405

Product page and current package options

ParameterValue
Chemical NameN2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine
CAS No.1578245-44-9
SynonymsBOS-172722;BOS 172722
FormulaC24H30N8O
M.Wt446.559
SMILESC(NC1=CC=C(C2N(C)C=NN=2)C=C1OCC)1=NC=C2C=C(C)N=C(NCC(C)(C)C)C2=N1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM.

In Vitro

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM. BOS-172722 also has potential for the treatment of various forms of breast cancer[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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