DC Chemicals · Product datasheet

Alflutinib — Datasheet

CAT. NO. DC12389

Product page and current package options

ParameterValue
Chemical NameN-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide
CAS No.1869057-83-9
SynonymsAST2818;AST-2818;ASK120067
FormulaC28H31F3N8O2
M.Wt568.605
SMILESC(NC1=CC(NC2=NC=CC(C3C4=C(N(C)C=3)C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(CCN(C)C)C)(=O)C=C
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Alflutinib (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation. Lung Cancer Phase 1 Clinical

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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