Luteolin 7-O-glucuronide (Luteolin 7-glucuronide4) Datasheet | DC12117

Luteolin 7-O-glucuronide (Luteolin 7-glucuronide4) — Datasheet

CAT. NO. DC12117

Parameter	Value
CAS No.	29741-10-4
Formula	C21H18O12
M.Wt	462.36
SMILES	O=C1C2=C(C=C(C=C2OC(C3=CC(O)=C(O)C=C3)=C1)O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)O
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

MMP-1:17.63 μM (IC50)

MMP-3:7.99 μM (IC50)

MMP-8:11.42 μM (IC50)

MMP-9:12.85 μM (IC50)

MMP13:0.03 μM (IC50)

References & source

[1]. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.