DC Chemicals · Product datasheet

E3 Ligand-Linker Conjugate 8 — Datasheet

CAT. NO. DC11574

Product page and current package options

ParameterValue
Chemical NameN-{2-2-(2-aminoethoxy)ethoxyethyl}-2-{2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yloxy}acetamide
CAS No.1957235-74-3
SynonymsE3 Ligand-Linker Conjugate 8;N-{2-2-(2-aminoethoxy)ethoxyethyl}-2-{2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yloxy}acetamide
FormulaC21H26N4O8
M.Wt462.453145503998
SMILESO=C1C(CCC(N1)=O)N1C(C2C=CC=C(C=2C1=O)OCC(NCCOCCOCCN)=O)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

An E3 ligase ligand-linker conjugate for PROTAC.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

References 1. Lohbeck J, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262. View Related Products by Target E3 Ligase Ligand-Linker Conjugate

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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