DC Chemicals · Product datasheet

Glumetinib — Datasheet

CAT. NO. DC11543

Product page and current package options

ParameterValue
Chemical Name6-(1-Methyl-1H-pyrazol-4-yl)-1-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]sulfonyl]-1H-pyrazolo[4,3-b]pyridine
CAS No.1642581-63-2
SynonymsSCC244;SCC 244
FormulaC21H17N9O2S
M.Wt459.488
SMILESC12C=NN(S(C3N4C(=NC=3)C=CC(C3=CN(C)N=C3)=C4)(=O)=O)C1=CC(C1=CN(C)N=C1)=CN=2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin[1].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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