DC Chemicals · Product datasheet

STING agonist compound 1 — Datasheet

CAT. NO. DC11451

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ParameterValue
Chemical NameDiabzi STING agonist-1
CAS No.2138299-33-7
SynonymsdiABZI STING agonist-1;STING agonist 3;diABZI STING agonist-1 (Tautomerism);Tautomerism;diABZI STING agonist-3;STING agonist compound 3;L7DUG75C36;GTPL10128;diABZI STING agonist(compound 3);diABZI STING agonist-1 Tautomerism;s8796;diABZI STING agonist 1 (compound 3);(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-
FormulaC42H51N13O7
M.Wt849.937247514725
SMILESO1CCN(CC1)CCCOC1=CC(C(N)=O)=CC2=C1N(C(NC(C1=CC(C)=NN1CC)=O)=N2)C/C=C/CN1C(NC(C2=CC(C)=NN2CC)=O)=NC2C=C(C(N)=O)C=C(C1=2)OC
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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