Seclidemstat（SP-2577） Datasheet | DC11400

Seclidemstat（SP-2577） — Datasheet

CAT. NO. DC11400

Parameter	Value
Chemical Name	N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]- 3-(4-methylpiperazine-1-sulfonyl)benzohydrazide
CAS No.	1423715-37-0
Synonyms	SP-2577,SP2577,SP 2577
Formula	C20H23ClN4O4S
M.Wt	450.93
SMILES	O=C(N/N=C(C1=CC(Cl)=CC=C1O)\C)C2=CC=CC(S(=O)(N3CCN(C)CC3)=O)=C2
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Seclidemstat (SP-2577) is a potent LSD1 inhibitor, with a mean IC50 of 127 nM.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

Seclidemstat (Compound 2577) reduces tumor volume at 40, 80 mg/kg by i.p. and also shows such effect at 80 mg/kg via p.o. dosing.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Seclidemstat（SP-2577） — Datasheet

Biological Activity

In Vitro

In Vivo

References & source

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