DC Chemicals · Product datasheet

CT7001(Samuraciclib hydrochloride） — Datasheet

CAT. NO. DC11303

Product page and current package options

ParameterValue
Chemical NameSamuraciclib hydrochloride
CAS No.1805789-54-1
SynonymsSamuraciclib hydrochloride;ICEC0942 HCl;YOH5NJ0DC3;Samuraciclib (hydrochloride);CT7001 hydrochloride;(3R,4R)-4-(((7-(Benzylamino)-3-isopropylpyrazolo[1,5-a]pyrimidin-5-yl)amino)methyl)piperidin-3-ol hydrochloride;ICEC0942 (CT7001);ICEC0942 hydrochloride;S8722;3-Piperidinol, 4-(((3-(1-methylethyl)-7-((phenylmethyl)amino)pyrazolo(1,5-a)pyrimidin-5-yl)amino)methyl)-, hydro
FormulaC22H31ClN6O
M.Wt430.974143266678
SMILESCl.O[C@H]1CNCC[C@@H]1CNC1C=C(NCC2C=CC=CC=2)N2C(=C(C=N2)C(C)C)N=1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

CT7001 hydrochloride is a selective CDK7 inhibitor, with IC50s of 41 nM and 578 nM for CDK7/CycH/MAT1 and CDK2/cycE1, respectively.

In Vitro

CT7001 (ICEC0942) is a selective CDK7 inhibitor, with IC50s of 41 nM and 578 nM for CDK7/CycH/MAT1 and CDK2/cycE1, respectively[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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