Biological Activity
SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability
In Vitro
SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability; reduces Txnip and Arrdc4 expression to a degree similar to that seen with SBI-477 in human myotubes; reduces muscle and liver TAG levels, enhances insulin signaling, and improved glucose tolerance in mice fed a high-fat diet.
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.