Biological Activity
rac-BHFF is a potent and orally active allosteric enhancer of GABAB receptor[1].
In Vitro
No in vitro data are provided in the current product source. Contact us for further information.
In Vivo
rac-BHFF has anxiolytic-like properties in stress-induced hyperthermia (SIH) in mice[1]. rac-BHFF (3, 10, 30 and 100 mg/kg, p.o.) reverses SIH and high significance was reached for 100 mg kg−1 (P<0.001)[1]. Animal Model: Male NMRI mice (20-25 g)[1]. Dosage: 3, 10, 30 or 100 mg/kg. Administration: P.O.. Result: Significantly increased the LRR effects of a subthreshold dose of baclofen at doses of 3 mg/kg and above.
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.