DC Chemicals · Product datasheet

GBT-440(Voxelotor) — Datasheet

CAT. NO. DC10474

Product page and current package options

ParameterValue
Chemical NameVoxelotor
CAS No.1446321-46-5
SynonymsGBT 440;Voxelotor;GBT-440;Voxelotor(GBT440, GTX011);Hemoglobin Modulators-1;3ZO554A4Q8;Voxelotor [USAN];Voxelotor (USAN);2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde;GBT440;FWCVZAQENIZVMY-UHFFFAOYSA-N;BCP20182;BDBM50235297;SB19656;2-hydroxy-6-[[2-(2-propan-2-ylpyrazol-3-yl)pyridin-3-yl]methoxy]benzaldehyde;AK547400;S8540;D11330
FormulaC19H19N3O3
M.Wt337.3725
SMILESO(C1=C([H])C([H])=C([H])C(=C1C([H])=O)O[H])C([H])([H])C1C([H])=C([H])C([H])=NC=1C1=C([H])C([H])=NN1C([H])(C([H])([H])[H])C([H])([H])[H]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

GBT 440 (Voxelotor) is an orally bioavailable modulator of sickle cell hemoglobin.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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