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Sterol lipids / Stigmasterol
Stigmasterol chemical structure
CAT. NO. DCD-042Featured

Stigmasterol

Pack size & price

USD
TotalUS$200
Ships from ShanghaiFor research use only
Product overview

Description & Application

Stigmasterol is an orally acitve, immunomodulatory agent with anti-inflammatory and neuroprotective effect, as well as able to cross the blood-brain barrier. Stigmasterol activates AMPK, which in turn inhibits NF-κB and NLRP3 signaling pathways, reduces microglia-mediated neuroinflammation, and alleviates cognitive impairment and Alzheimer's disease. Stigmasterol regulates M1/M2 polarization of microglia through the TLR4/ NF-κB pathway, thereby reducing neuropathic pain. Stigmasterol can be used for neurodegenerative diseases, inflammatory diseases, and pain management, among others.

CAS No.83-48-7
Chemical NameStigmasterol
SynonymsStigmasterol;3BETA-HYDROXY-24-ETHYL-5,22-CHOLESTADIENE;[3B-HYDROXY-24-ETHYL-D] ZZ-CHOLESTADIENE;5,22-STIGMASTADIEN-3-BETA-OL;5,22-CHOLESTADIEN-24B-ETHYL-3BETA-OL;5,22-CHOLESTADIEN-24BETA-ETHYL-3BETA-OL;(24S)-5,22-STIGMASTADIEN-3BETA-OL;STIGMASTERIN;Stigmasta-5,22-dien-3-ol,(3b,22E)-;STIGMASTEROL(AS);STIGMASTEROL(P) PrintBack;(3β,22E)-StigMasta-5,22-dien-3-ol;22-Dehydro-24-ethylcholesterol;24S-ethylcholest-5,22-dien-3β-ol;3β-Hydroxy-24-ethyl-5,22-cholestadiene;5,22-stigmastadien-3β-ol;5,22-StigMastadiene-3β-ol;Anti-stiffness factor;isofucosterol;PHYTOSTEROL;stigmasta-5,22-dien-3β-ol;Stigmastero;STIGMASTEROL (STIGMASTERIN);STIGMASTEROL(P);SULFISOXAZOLE;Stigmasta-5,22-dien-3beta-ol;Stigmasta-5;[ "Stigmasta-5", "22-dien-3-ol" ];110801;beta-Stigmasterol;D5-Stigmasterol;Stigmasterin; Phytosterol; beta-Stigmasterol; D5-Stigmasterol; 110801;(3β,22E)-Stigmasta-5,22-dien-3-ol (ACI);Stigmasta-5,22-dien-3β-ol (8CI);(24S)-24-Ethylcholesta-5,22-dien-3β-ol;(24S)-5,22-Stigmastadien-3β-ol;(24S)-Stigmast-5,22-dien-3β-ol;24-Ethyl-5,22-cholestadien-3β-ol;24β-Ethyl-5,22-cholestadien-3β-ol;MeSH ID: D013265;NSC 8095;Stigmasta-5,22(E)-dien-3β-ol;β-Stigmasterol;Δ5,22-Stigmastadien-3β-ol;Δ5-Stigmasterol
SMILESC[C@@]12[C@@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)CC[C@H]1[C@@H]1CC=C3C[C@H](CC[C@]3(C)[C@H]1CC2)O
FormulaC29H48O
M.Wt412.690829277039
Purity>98%, Standard References Grade
Storage4°C for 1 year, -20°C for more than 2 years
Shipping conditionShips from Shanghai; pack and transport conditions confirmed at order.
PublicationNot available
Product classificationSterol lipids
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg24.2312 mL4.8462 mL2.4231 mL
25 mg60.5780 mL12.1156 mL6.0578 mL
50 mg121.1561 mL24.2312 mL12.1156 mL
100 mg242.3121 mL48.4624 mL24.2312 mL
250 mg605.7804 mL121.1561 mL60.5780 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage from the old product catalog: 4°C for 1 year, -20°C for more than 2 years Keep sealed and protected from light.
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.