KRN-7000(S34)
DC67239
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BAY 11-7082 is a NF-κB inhibitor which decreases NF-κB by inhibiting TNF-α-induced phosphorylation of IκB-α. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50s of 0.19 μM and 0.96 μM, respectively.
| CAS No. | 19542-67-7 |
| Chemical Name | (E)-3-Tosylacrylonitrile |
| Synonyms | (E)-3-Tosylacrylonitrile;BAY 11-7082;(E)?-?3-?(p-?Toluenesulfonyl)?acrylonitrile;(E)-3-(4-methylphenyl)sulfonylprop-2-enenitrile;(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE;Bay 11-7082 (Bay 11-7821);BAY 11-7821;BAY-11-7082;(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile;BAY 117821;BAY11-7082,BAY 117821;(E)-3-(p-tolylsulfonyl)prop-2-enenitrile;(2E)-3-[(4-METHYLPHENYL)SULFONYL]-2-PROPENENITRILE;BAY117082;4Y5G2A4F6O;3-(4-methylphenylsulfonyl)-2-propenenitrile;3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile;(E)3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile;(2E)-3-[(4 |
| SMILES | S(/C(/[H])=C(\[H])/C#N)(C1C([H])=C([H])C(C([H])([H])[H])=C([H])C=1[H])(=O)=O |
| Formula | C10H9NO2S |
| M.Wt | 207.249 |
| Purity | 98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Adjuvant Molecules |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 48.2511 mL | 9.6502 mL | 4.8251 mL |
| 25 mg | 120.6278 mL | 24.1256 mL | 12.0628 mL |
| 50 mg | 241.2557 mL | 48.2511 mL | 24.1256 mL |
| 100 mg | 482.5114 mL | 96.5023 mL | 48.2511 mL |
| 250 mg | 1206.2784 mL | 241.2557 mL | 120.6278 mL |
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