Tasquinimod is an oral antiangiogenic agent in clinical trials for the treatment of castration-resistant prostate cancer. Tasquinimod binds to the regulatory Zn2+ binding domain of HDAC4 with Kd of 10-30 nM.
| CAS No. | 254964-60-8 |
| Chemical Name | ABR-215050; ABR215050; ABR 215050 |
| Synonyms | ABR-215050; ABR215050; ABR 215050 |
| SMILES | CN1C2=C(C(=CC=C2)OC)C(=C(C1=O)C(=O)N(C)C3=CC=C(C=C3)C(F)(F)F)O |
| Formula | C20H17F3N2O4 |
| M.Wt | 406.36 |
| Purity | Not available |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Adjuvant Molecules |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 24.6087 mL | 4.9217 mL | 2.4609 mL |
| 25 mg | 61.5218 mL | 12.3044 mL | 6.1522 mL |
| 50 mg | 123.0436 mL | 24.6087 mL | 12.3044 mL |
| 100 mg | 246.0872 mL | 49.2174 mL | 24.6087 mL |
| 250 mg | 615.2180 mL | 123.0436 mL | 61.5218 mL |
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