Cholesterol
DCD-041
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SCS is an orally active cholesterol biosynthesis agonist that targets NPC2. It activates SREBP2 by competitively binding to NPC2, thereby promoting cholesterol synthesis (EC50 = 50 μM).
| CAS No. | 2864-50-8 |
| Chemical Name | Cholesterol 3-Sulfate Sodium Salt |
| Synonyms | Cholesteryl sodium sulfate;Sodium cholesteryl sulfate;5-Cholesten-3beta-ol sulfate sodium salt;Cholesterol-3-sulfate sodium salt;cholesterol 3-sulfate (sodium salt);Cholesterol 3-Sulfate Sodium Salt;Cholesterol Sulfate (sodium salt);5-Cholesten-3β-ol sulfate sodium salt;Cholesteryl sulfate sodium salt;cholesterol sulfonate;cholesteryl sulfate;cholesteryl sulphate;cholesterol sulfonate; cholesteryl sulfate; sodium cholesteryl sulfate; cholesteryl sulphate |
| SMILES | O=S(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@@H](CCCC(C)C)C)CC[C@@]4([H])[C@]3([H])CC=C2C1)([O-])=O.[Na+] |
| Formula | C27H45O4S-.NA+ |
| M.Wt | 488.6986 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; pack and transport conditions confirmed at order. |
| Publication | Not available |
| Product classification | Sterol lipids |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 20.4625 mL | 4.0925 mL | 2.0463 mL |
| 25 mg | 51.1563 mL | 10.2313 mL | 5.1156 mL |
| 50 mg | 102.3126 mL | 20.4625 mL | 10.2313 mL |
| 100 mg | 204.6251 mL | 40.9250 mL | 20.4625 mL |
| 250 mg | 511.5628 mL | 102.3126 mL | 51.1563 mL |
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