AYK004 is a TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. AYK004 is an adenine derivative with a favorable hydrophilic-lipophilic balance, which improves the loading capacity and stability in immunoadjuvant systems such as liposomes, while reducing the side effects of the immunoadjuvant system in systemic immunity .
| CAS No. | 3031612-90-2 |
| Chemical Name | AYK004 |
| Synonyms | Not available |
| SMILES | O=C1NC2=C(N1CCCCCN3CCNCC3)N=C(OC(C(F)(F)F)C)N=C2N |
| Formula | C17H26F3N7O2 |
| M.Wt | 417.43 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Adjuvant Molecules |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 23.9561 mL | 4.7912 mL | 2.3956 mL |
| 25 mg | 59.8903 mL | 11.9781 mL | 5.9890 mL |
| 50 mg | 119.7806 mL | 23.9561 mL | 11.9781 mL |
| 100 mg | 239.5611 mL | 47.9122 mL | 23.9561 mL |
| 250 mg | 598.9028 mL | 119.7806 mL | 59.8903 mL |
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