DSPE-PEG-CHO

Description & Application

DSPE phospholipids can be used as pharmaceutical excipients for emulsification and drug solubilization, and are important materials for slow release drug preparations such as liposomes, fat milk and nanoparticles in recent years. Modification of phospholipid molecules can make these preparations have the ability of release and targeting under specific conditions. Common modification methods include: disintegration time; Introducing immune factors to enhance targeting; Introduce markers for diagnosis and tracking. A covalent bond in the carbonyl group is connected to the hydrogen atom and formed by a univalent atomic group, called aldehyde group, aldehyde group structure simple formula is -CHO, aldehyde group is a hydrophilic group, so the organic matter with aldehyde group (such as acetaldehyde, etc.) has a certain water solubility. Aldehydes, sugars, aldehydes, glucose, maltose and other molecules contain aldehyde groups. The aldehydes are active and prone to condensation and nucleophilic addition reactions. The aldehyde group can be reduced to hydroxymethyl (-CH2OH) or oxidized to carboxylic (-COOH).