KRN-7000(S34)
DC67239
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TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4, linked via the cleavable ADC linker hydroxy-PEG10-acid.
| CAS No. | 2388520-36-1 |
| Chemical Name | TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride |
| Synonyms | 4,7,10,13,16,19,22,25,28,31-Decaoxatritriacontanoic acid, 33-[4-(4-amino-2-butyl-3H-imidazo[4,5-c]quinolin-8-yl)-1-piperazinyl]-, hydrochloride (1:1) |
| SMILES | C12NC(CCCC)=NC1=C1C(=NC=2N)C=CC(N2CCN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)CC2)=C1.Cl |
| Formula | C41H69ClN6O12 |
| M.Wt | 873.47 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Adjuvant Molecules |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 11.4486 mL | 2.2897 mL | 1.1449 mL |
| 25 mg | 28.6215 mL | 5.7243 mL | 2.8621 mL |
| 50 mg | 57.2430 mL | 11.4486 mL | 5.7243 mL |
| 100 mg | 114.4859 mL | 22.8972 mL | 11.4486 mL |
| 250 mg | 286.2148 mL | 57.2430 mL | 28.6215 mL |
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